Exclusive breastfeeding is essential to the growth and development of infants especially for the first six months of their life. Nursing mothers are therefore encouraged to adhere to this practice to promote the health of infants and their own health. Exclusive breastfeeding can also be economical since the mother and significant individuals in the family will not spend much money on artificial infant feeds. This book outlines the importance of exclusive breastfeeding through the review of related literature and examined some determinants of exclusive breastfeeding in Ghana. The book will be a good reference guide to those interested in exclusive breastfeeding including students, public health experts and policy makers.